Services |  Antibody Humanization service

We offer antibody humanization services that maintain or improve affinity while ensuring low immunogenicity for therapeutic applications. Please complete the form to request a quote.

Antibody Humanization with 5 Methods

To maximize the probability of success, we will humanize the antibody VL and VH sequences using five different strategies. This resulted in five humanized VH and five humanized VL sequences which will be combined to generate a total of 25 humanized antibodies.

Structure of antibody VH

The amino acids (AA) to be humanized are highlighted in green.

Humanized Antibody Activity

All completed humanized antibody projects have demonstrated affinity levels equal to or higher than the parental antibody's.

Humanized Antibody Activity Restoring Service

We restored the humanized antibody activity in a failed humanization project conducted by another company. Restoring the activity of a humanized antibody is not simply reverting to the amino acids of the murine antibody. It requires individual analysis for each specific case. We successfully restored the antibody activity and received positive feedback from our customer.